A modern standard in efficacy: testing required

Maintaining good skin health is a holistic endeavor — everything one consumes is as integral as what one applies to the skin. However, the uptake of nutrients in the digestive system is complicated, and research about the efficacy of skincare supplements is often inconclusive [1].

Our objective is to elevate supplement science to achieve higher levels of efficacy.

Tiny Associates proposes the Niiice is testing™ standard as a modern standard in efficacy.

The new supplement standard: testing required

Skincare supplements could be more dependable if two product-testing requirements are met:


1. Product quality
/ amount of bioactive compound(s)

2. Product bioavailability

The new supplement standard: testing required

Skincare supplements could be more dependable if two product-testing requirements are met:


1. Product quality
/ amount of bioactive compound(s)

2. Product bioavailability

Supplements are only as good as their amount of active compound(s)

Ingredients and their active compounds does not guarantee that a final product will be effective. While peer-reviewed studies may provide evidence for the effectiveness of certain ingredients, several factors influence the effectiveness of the final products, such as formulation, reactivity of other compounds in the product and the method of delivery. For this reason, Tiny Associates conducts laboratory tests to assess the amount of active compounds present in the final products.

Supplements are only as good as their amount of active compound(s)

Ingredients and their active compounds does not guarantee that a final product will be effective. While peer-reviewed studies may provide evidence for the effectiveness of certain ingredients, several factors influence the effectiveness of the final products, such as formulation, reactivity of other compounds in the product and the method of delivery. For this reason, Tiny Associates conducts laboratory tests to assess the amount of active compounds present in the final products.

Amount of bioactive compound(s) does not matter without bioavailability

In contrast to topical skincare products, skincare supplements and their bioactive compound(s) must go through a much more complicated delivery process. They must pass through the gastrointestinal tract, cross the intestinal barrier, enter blood circulation and then be distributed to the target tissue, the skin. When supplements adhere to this process, scientists call them bioavailable.

To meet this criteria, Tiny Associates laboratory tests the supplements for bioavailability, ensuring they can be disintegrated — a prerequisite for bioactive compounds to be available for absorption.

Amount of bioactive compound(s) does not matter without bioavailability

In contrast to topical skincare products, skincare supplements and their bioactive compound(s) must go through a much more complicated delivery process. They must pass through the gastrointestinal tract, cross the intestinal barrier, enter blood circulation and then be distributed to the target tissue, the skin. When supplements adhere to this process, scientists call them bioavailable.

To meet this criteria, Tiny Associates laboratory tests the supplements for bioavailability, ensuring they can be disintegrated — a prerequisite for active compounds to be available for absorption.

Discovering the Link Between Nutrition and Skin Aging Silke K. Schagen, 1 , † Vasiliki A. Zampeli, 1 , 2 , † Evgenia Makrantonaki, 1 , 2 and Christos C. Zouboulis 1 ,* Dermatoendocrinol. 2012 Jul 1; 4(3): 298–307.